Description
GLP RT3 is a research material commonly used as a reference standard or experimental reagent in controlled laboratory settings. Typical use cases include receptor-binding and cAMP functional assays, comparative incretin pharmacology, analytical method development, and non-clinical in vitro workflows.
Reported in vitro potency at the human receptors is markedly unbalanced across the three targets: EC50 values of approximately 0.064 nM at GIPR, 0.775 nM at GLP-1R, and 5.79 nM at GCGR in cAMP assays — roughly a 90-fold spread. This asymmetry is central to how the compound is characterized in comparative pharmacology work.
Documentation such as COA, HPLC chromatograms, and LC-MS data may be available on a lot basis where applicable. Request documentation by emailing connect@novuspeptides.com with the catalog number and required tests.
This product is sold strictly for laboratory research use only and is not intended for human or veterinary administration. Buyer is responsible for lawful handling, storage, and use in accordance with all applicable regulations.
Technical Summary
- Catalog #:GLP RT3
- Form:Lyophilized Powder
- Purity:≥ 99%
- Verification:HPLC / LC-MS
- CAS Number:2381089-83-2
- Molecular Weight:4731.33 g/mol
- Molecular Formula:C221H343N53O67
- Synonyms:LY3437943, LY-3437943
- Appearance:White Lyophilized Powder
- Structure:39 amino acids; Aib at positions 2 and 20; α-methyl-Leu at position 13; C20 fatty diacid via γ-Glu spacer
